严重的皮肤问题可以用 "severe skin condition" 或 "serious skin problem" 来表示。
皮肤问题的来源可能有很多，包括遗传因素、环境因素、药物副作用、感染或免疫系统问题等。例如：
Acne is a common skin condition that is caused by hormonal changes, genetics, and other factors. (粉刺是一种常见的皮肤问题，主要由激素变化、遗传因素和其他因素引起。)
Eczema is a chronic skin condition that is characterized by itchy, red, and inflamed skin. It can be triggered by stress, allergies, or other factors. (湿疹是一种慢性皮肤病，以瘙痒、红肿、发炎的皮肤为特征。它可能由压力、过敏或其他因素引起。)
Psoriasis is a autoimmune disorder that causes cells to build up rapidly on the surface of the skin, resulting in red, scaly patches. (牛皮癣是一种免疫系统紊乱，导致皮肤表面的细胞快速堆积，导致皮肤出现红色、鳞状斑块。)
Rosacea is a skin condition that causes redness and visible blood vessels in the face. It can be triggered by stress, alcohol, and certain foods. (玫瑰痤疮是一种皮肤病，会导致面部出现红色和可见的血管。它可能由压力、酒精和某些食物引起。)