精疲力尽用英语常用的短语是 "exhausted" 或 "worn out"。
"Exhausted" 来源于拉丁语 "exhaustus"，意思是 "耗尽的" 或 "疲惫的"。"Worn out" 来源于中古英语 "weorn"，意思是 "磨损的" 或 "疲惫的"。
下面是一些英文例句和中文翻译：
After working for 12 hours straight, I was completely exhausted. (我连续工作了12个小时，现在精疲力尽。)
I'm so worn out from all the travepng that I can barely keep my eyes open. (我因为旅行太多而疲惫不堪，几乎眼睛都睁不开了。)
She was exhausted from caring for her sick child. (她因为照顾生病的孩子而精疲力尽。)
The old, worn out couch was finally replaced with a new one. (那张旧的磨损的沙发终于被换成了一张新的。)