"Annoying" or "irritating" are Engpsh words that can describe the meaning of "烦人".
It comes from the verb "annoy", which means to cause trouble, vexation, or irritation.
Examples in Engpsh with Chinese translation:
His constant complaining is really annoying.
他不停的抱怨真的很烦人。
The traffic jam was irritating and made me late for my meeting.
交通堵塞很烦人，让我迟到了。