"主要负责"这个短语的英文表达是 "mainly responsible for"。这个短语是由两个单词"mainly" 和 "responsible"组合而成的。
"mainly" 意为 "主要地"，是一个副词。
"responsible" 意为 "负责的"，是一个形容词。
例句：
He is mainly responsible for the company's financial decisions. 他主要负责公司的财务决策。
She is mainly responsible for organizing the event. 她主要负责组织这个活动。
The project manager is mainly responsible for overseeing the project's progress. 项目经理主要负责监督项目的进度。